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60 Investor presentation Full year 2022 More than 764 million people are narrative is changing Obesity is a global epidemic affecting more than 764 million people 1 Obesity impacts bot society a Obesity is ass > 200 possi complic ~ 3% of globa >8% of health per cou Obesity prevalence (%) <10.0 10.0 – 19.9 20.0 – 29.9 ≥30.0 Not applicable Note: Obesity is defined as BMI > 30. PwO: People with obesity 1 World Obesity Atlas 2022 2 Yuen M., Earle R., Kadambi N., et al. A systematic review and evaluation of current evidence reveals 236 Dobbs R, Sawers C, Thompson F, et al. Overcoming Obesity: An Initial Economic Analysis. McKinsey Global Institute.

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e living with obesity, yet the Novo Nordisk ® th the individual and at large sociated with ible health cations 2 al GDP and hcare budget untry 3 The obesity narrative is changing Media: Shift to more empathetic tone Healthcare professionals: Increased recognition among societies within healthcare Policymakers: More government recognition People with obesity: Patient groups are encouraging PwO to seek treatment 6 Obesity-Associated Disorders (OBAD). Massachusetts General Hospital & George Washington University. [Poster presentation]; 3

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