21 Investor presentation First nine months of 2023 Novo Nordisk’s opportunity is in t therapy areas in scope Diabetes care 537m people with diabetes 1 ~15% of people in good control 2 Rare disease Haemophilia 0.6m people with haemophilia 4 ~35% of people being treated 1 International Diabetes Federation: Diabetes Atlas 10 th edition, 2021; 2 Real-world studies indicate between 30-55% of patients reach Hb Diabetes Atlas 2022; 4 WFH annual survey 2020 (120 of 147 countries responded): Prevalence by calculating expected number of pa causes of death” , WHO, 9 December 2020 (ASCVD denoted as ischaemic heart disease); 6 Groenewegen A et al. Eur J Heart Fail 2020 demonstrates an exponential increase in burden of disease, Hepatology, 2018; 8 The World Alzheimer Report 2015, The Global Impa
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