75 Investor presentation First three months of 2021 Novo Nordisk is expanding into o Serious chronic diseases are often associated with diabetes and obesity AD • Patients with AD live from 2 to 20 years from dementia onset CVD • 70% of people with diabetes die from atherosclerotic CVD • 40% of people hospitalised for heart failure have diabetes NASH • 80% of people with NASH live with obesity and 35% have diabetes CKD • 40% of people with diabetes have diabetic nephropathy and 50% have obesity 1 Internal forecast comprising the USA, Europe and Japan; 2 Diagnosis rate is considered a major uncertainty to the forecast CVD: Cardiovascular disease; NASH: Non- alcoholic Steatohepatitis; CKD: Chronic kidney disease; AD: Alzheimer’s disease Sources: Alzheimer’s Association report: 2020 Alzheimer’s disease facts and figures, 2020 (16:391 -460), Diabetes Care 2005 Jan; 28 Heart Disease and Stroke Statistics, American Heart Association, 2017; Williams CD et al. Prevalence of nonalcoholic fatty liver dise Addressing the global burden of chronic kidney disease through clinical and translational research, 2014
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